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Essential role for Abi1 in embryonic survival and WAVE2 complex integrity.
Dubielecka PM, Ladwein KI, Xiong X, Migeotte I, Chorzalska A, Anderson KV, Sawicki JA, Rottner K, Stradal TE, Kotula L. Dubielecka PM, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7022-7. doi: 10.1073/pnas.1016811108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482783 Free PMC article.
To gain a better understanding of the specific role of Abi1, we generated a conditional Abi1-KO mouse model and MEFs lacking Abi1 expression. ...Cells lacking Abi1 and the conditional Abi1-KO mouse will serve as critical models for defining A …
To gain a better understanding of the specific role of Abi1, we generated a conditional Abi1-KO mouse model and MEFs lacking …
Transcriptome-wide analysis reveals the coregulation of RNA-binding proteins and alternative splicing genes in the development of atherosclerosis.
Wang R, Xu J, Tang Y, Wang Y, Zhao J, Ding L, Peng Y, Zhang Z. Wang R, et al. Sci Rep. 2023 Jan 31;13(1):1764. doi: 10.1038/s41598-022-26556-6. Sci Rep. 2023. PMID: 36720950 Free PMC article.
Meanwhile, we found seven regulated alternative splicing genes (RASGs) (ABI1, FXR1, CHID1, PLEC, PRKACB, BNIP2, PPP3CB) that could be regulated by RBPs. ...
Meanwhile, we found seven regulated alternative splicing genes (RASGs) (ABI1, FXR1, CHID1, PLEC, PRKACB, BNIP2, PPP3CB) that could be …
[Evaluation of diagnostic efficacy of artery elasticity and endothelial function indexes for coronary heart disease with blood stasis syndrome in postmenopausal women by Logistic regression combined with ROC curve model].
Tao SY, Yu LT, Wang ZH, Chen Y, Zhang J, Yang DS, Huang L. Tao SY, et al. Zhongguo Zhong Yao Za Zhi. 2022 Apr;47(8):2244-2250. doi: 10.19540/j.cnki.cjcmm.20211201.501. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 35531741 Chinese.
The present study explored the correlation of coronary heart disease(CHD) with blood stasis syndrome in postmenopausal women with artery elasticity and endothelial function indexes and evaluated the diagnostic efficacy of the prediction model via logistic regression and re …
The present study explored the correlation of coronary heart disease(CHD) with blood stasis syndrome in postmenopausal women with art …
Optimized Cytogenetic Risk-Group Stratification of KMT2A-Rearranged Pediatric Acute Myeloid Leukemia.
van Weelderen RE, Harrison CJ, Klein K, Jiang Y, Abrahamsson J, Alonzo T, Aplenc R, Arad-Cohen N, Bart-Delabesse E, Buldini B, De Moerloose B, Dworzak MN, Elitzur S, Fernández Navarro JM, Gamis AS, Gerbing RB, Goemans BF, de Groot-Kruseman HA, Guest EM, Ha SY, Hasle H, Kelaidi C, Lapillonne H, Leverger G, Locatelli F, Miyamura T, Noren-Nystrom U, Polychronopoulou S, Rasche M, Rubnitz JE, Stary J, Tierens A, Tomizawa D, Zwaan MC, Kaspers GJL. van Weelderen RE, et al. Blood Adv. 2024 Apr 15:bloodadvances.2023011771. doi: 10.1182/bloodadvances.2023011771. Online ahead of print. Blood Adv. 2024. PMID: 38621200
Multivariable analyses confirmed independent associations of 4q21/KMT2A::AFF1, 6q27/KMT2A::AFDN, 10p12/KMT2A::MLLT10, 10p11.2/KMT2A::ABI1, and 19p13.3/KMT2A::MLLT1 with adverse outcomes, but not those of 1q21/KMT2A::MLLT11 and trisomy 19 with favorable and adverse outcomes …
Multivariable analyses confirmed independent associations of 4q21/KMT2A::AFF1, 6q27/KMT2A::AFDN, 10p12/KMT2A::MLLT10, 10p11.2/KMT2A::ABI1 …
New perspectives on the roles of Abl tyrosine kinase in axon patterning.
Kannan R, Giniger E. Kannan R, et al. Fly (Austin). 2017 Oct 2;11(4):260-270. doi: 10.1080/19336934.2017.1327106. Epub 2017 May 8. Fly (Austin). 2017. PMID: 28481649 Free PMC article. Review.
The Abelson tyrosine kinase (Abl) lies at the heart of one of the small set of ubiquitous, conserved signal transduction pathways that do much of the work of development and physiology. ...
The Abelson tyrosine kinase (Abl) lies at the heart of one of the small set of ubiquitous, conserved signal transduction pathways tha …
Combination of high ankle-brachial index and hard coronary heart disease Framingham Risk Score in predicting the risk of ischemic stroke in general population.
Zhang Y, Chen J, Zhang K, Wang T, Kong M, Chen R, Liu Y, Chen J, Wang Z, Wang J, Huang H. Zhang Y, et al. PLoS One. 2014 Sep 8;9(9):e106251. doi: 10.1371/journal.pone.0106251. eCollection 2014. PLoS One. 2014. PMID: 25198106 Free PMC article.
This study aims to evaluate this association in the general population. 1486 subjects of South China were recruited in the study. 61 subjects were defined as high ABI group (ABI1.3) and 65 subjects were randomly selected as normal ABI group (0.9<ABI<1.3). Biochemical …
This study aims to evaluate this association in the general population. 1486 subjects of South China were recruited in the study. 61 subject …
The high normal ankle brachial index is associated with left ventricular hypertrophy in hypertension patients among the Han Chinese.
Sun J, Wang S, Li M, Su Y, Ma S, Zhang Y, Zhang A, Cai S, Cheng B, Bao Q, Zhu P. Sun J, et al. J Clin Hypertens (Greenwich). 2021 Sep;23(9):1758-1766. doi: 10.1111/jch.14328. Epub 2021 Jul 23. J Clin Hypertens (Greenwich). 2021. PMID: 34297892 Free PMC article.

Our study suggested that the ABI was higher in patients with LVH than in those without (1.130.11, 1.110.11, p < 0.001). The prevalence of LVH in patients with the lowest (0.9 < ABI1.03), second (1.04ABI1.11), the third (1.12ABI1.20), and the highest quartile (1.21ABI

…

Our study suggested that the ABI was higher in patients with LVH than in those without (1.130.11, 1.110.11, p < 0.001). The prevalence of

…
Gender-specific risk factors for peripheral artery disease in a voluntary screening population.
Hiramoto JS, Katz R, Weisman S, Conte M. Hiramoto JS, et al. J Am Heart Assoc. 2014 Mar 13;3(2):e000651. doi: 10.1161/JAHA.113.000651. J Am Heart Assoc. 2014. PMID: 24627420 Free PMC article.
Women were slightly older than men, whereas men were more likely to be current smokers, have diabetes mellitus (DM), and coronary artery disease (CAD) (P<0.001 for each). Women were more likely to have ABI1.0, compared to men (26.6% versus 14.4%, respectively; P<0.00 …
Women were slightly older than men, whereas men were more likely to be current smokers, have diabetes mellitus (DM), and coronary artery dis …
Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo.
Law AL, Vehlow A, Kotini M, Dodgson L, Soong D, Theveneau E, Bodo C, Taylor E, Navarro C, Perera U, Michael M, Dunn GA, Bennett D, Mayor R, Krause M. Law AL, et al. J Cell Biol. 2013 Nov 25;203(4):673-89. doi: 10.1083/jcb.201304051. Epub 2013 Nov 18. J Cell Biol. 2013. PMID: 24247431 Free PMC article.